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Volume 07 Issue 06 June 2024

Factors Affecting Extrapulmonary Tuberculosis Reinfection in Pulmonary Tuberculosis Patients in Gorontalo City
1Muh. Arfah Syam , 2Margaretha Solang ,3Widy Susanti Abdulkadir
1,2,3Department of Public Health, Postgraduate, Gorontalo State University, Gorontalo City
DOI : https://doi.org/10.47191/ijmra/v7-i06-20

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ABSTRACT:

Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis. Tuberculosis does not only occur in the lungs, which is called pulmonary tuberculosis but can occur outside the lung organs, which is called extrapulmonary tuberculosis. Reinfection from Pulmonary tuberculosis to Extrapulmonary tuberculosis can occur due to several factors. This study aims to determine the factors that can influence the occurrence of reinfection Extrapulmonary tuberculosis in pulmonary tuberculosis sufferers. Method Analytical research with a cross-sectional approach. The number of samples was 49 samples of Pulmonary tuberculosis sufferers who underwent initial diagnosis at the Anatomical Pathology Laboratory, Prof. Dr. Hi. Aloei Hospital. Saboe Gorontalo City. The results of the study showed that the variables Adherence to treatment (p: 0.047), and BCG Vaccine (p: 0.018) were < α value: 0.05, while the significance value of comorbidity for EPTB Reinfection was (p: 0.991). The conclusion is that adherence to treatment and the BCG vaccine have a significant effect on the incidence of reinfection Extrapulmonary tuberculosis (EPTB) in patients with pulmonary tuberculosis (PTB), while comorbidities do not have a significant effect on the incidence of reinfection Extrapulmonary tuberculosis (EPTB) in patients with pulmonary tuberculosis (PTB).

KEYWORDS:

Tuberculosis, Extrapulmonary tuberculosis, Pulmonary tuberculosis.

REFERENCES
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2) Barreto, M. L., Pereira, S. M., Pilger, D., Cruz, A. A., Cunha, S. S., Sant’Anna, C., Ichihara, M. Y., Genser, B., & Rodrigues, L. C. (2011). Evidence of an effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: Second report of the BCG-REVAC cluster-randomised trial. Vaccine, 29(31), 4875–4877. https://doi.org/10.1016/j.vaccine.2011.05.023

3) Bhattacharya, P., Talukdar, K., Barman, B., Jamil, M., Phukan, P., Mobing, H., War, G., Nonglait, P. L., Murti, S., Prithviraj, K., & Sangma, B. (2020). Clinical Spectrum and Medical Comorbidities in Tuberculosis: A Hospital-Based Study in Northeast India. Cureus, 12(9). https://doi.org/10.7759/cureus.10580

4) Central TBC Division. (2023). Training Module On Extrapulmonary Tuberculosis.

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6) Houda Ben, A., Makram, K., Chakib, M., Khaoula, R., Fatma, H., Fatma, S., Mariem Ben, H., Sourour, Y., Imed, M., Jamel, D., & Mounir Ben, J. (2018). Extrapulmonary Tuberculosis: Update on the Epidemiology, Risk Factors and Prevention Strategies. International Journal of Tropical Diseases, 1(1), 1–6. https://doi.org/10.23937/ijtd-2017/1710006

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9) Qian, X., Nguyen, D. T., Lyu, J., Albers, A. E., Bi, X., & Graviss, E. A. (2018). Risk factors for extrapulmonary dissemination of tuberculosis and associated mortality during treatment for extrapulmonary tuberculosis article. Emerging Microbes and Infections, 7(1). https://doi.org/10.1038/s41426-018-0106-1

10) Setiani, L. A., Almasyhuri, & Hidayat, A. A. (2022). Evaluasi Kepatuhan Pasien Pada Penggunaan Obat Antidiabetik Oral Dengan Metode Pill-Count dan MMAS-8 Di Rumah Sakit PMI Kota Bogor. Jurnal Ilmiah Ilmu Terapan Universitas Jambi, 6(1), 32–46.

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Volume 07 Issue 06 June 2024

There is an Open Access article, distributed under the term of the Creative Commons Attribution – Non Commercial 4.0 International (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits remixing, adapting and building upon the work for non-commercial use, provided the original work is properly cited.


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